Australian researchers find how humans kill new coronaviruses

According tomedia BGR reported that the new coronavirus pandemic is far from contained, the world reported more and more confirmed cases. Everyone should step up their efforts to “flatten the curve” – keeping social distance and washing their hands will help solve the problem. Doctors around the world need time to treat seriously ill patients, and some of their peers are trying to develop vaccines or new drugs to speed up the healing process. The good news for people infected with the new coronavirus is that most people recover because of the body’s immune system.

Researchers in Australia have figured out how the human body kills the SARS-CoV-2 virus, and their early results will help others develop new treatments that could boost immunity and even eradicate the disease.

Australian researchers have found that the human body fights the disease in the same way as it does the common flu. This conclusion is provisionally applicable to patients with mild or moderate symptoms, so that a full recovery can be made. It is not clear how long immunity will last, and there is no guarantee that once cured, the body will not be re-infected with the same COVID-19 disease.

“Before the patient recovers, we’ve seen the same immune cell population as we see in the flu,” Katherine Kedzierska, the lab’s director, told the Australian Broadcasting Corporation. This information will allow us to evaluate any candidate vaccine, because in an ideal world the vaccine should mimic the body’s immune response. “

Australian researchers find how humans kill new coronaviruses

Researchers at the Peter Doherty Institute for Infection and Immunization are among the first in the world to explain the immune system’s response to coronaviruses as they prepare for the threat for years. The Research Readiness Platform, led by infectious disease expert Irani Thevarajan, has developed the logistics needed to respond to new viruses as quickly as possible. Existing protocols help them conduct research quickly, saving valuable time. “Sometimes delays can take months, and from patient to patient study it can’t be completed in four weeks,” she said. “

Researchers analyzed blood samples from a 40-year-old woman who was one of Australia’s first coronavirus patients and was admitted to hospital after a trip to Wuhan with symptoms including drowsiness, sore throat, dry cough and fever. “We found the patient three days later and we could see immune cells in the blood,” Kedzierska said. Based on our experience in influenza patients, we can predict their recovery, which is exactly what happens in COVID-19. “

In addition to developing vaccines, the new findings could also help doctors determine a patient’s condition. Markers in the blood can be used to see if a patient develops more severe symptoms, which may be a key achievement in the fight against COVID-19. The doctor will be able to tell the patient in advance whether the condition is serious or mild, and then take appropriate action.

Governments around the world are trying to limit the spread of the disease because of severe cases that must be entered into hospitals, and treatments such as intubation and ventilation must be used. The more people infected, the more serious cases they need to be in intensive care. That’s the kind of thing that could cause the local health care system to collapse. Scientists will also analyze the immune system’s response in severe COVID-19 cases in search of new treatments.

Professor Kedzierska also noted that it was too early to say how effective the immunization soutcomes would be. “The next question is whether the immune response can keep people immune for weeks, months or years, so we’re protected,” she said. “But the answer will not come out until the next few months, as researchers are examining recovering patients.

CoVID-19 coronavirus research at the Peter Doherty Institute for Infection and Immunization has been published in the journal Nature Medicine.