Hospitals often use a chemical extracted from blood when using special equipment to monitor for germs that can lead to sepsis. The blood of the Atlantic horseshoe crab (Limulus polyphemus) contains an amoeba immune cell that produces a substance called the moth-deformed cell solubility ( LAL). The chemical is highly sensitive to polysaccharide toxins produced by Gram-negative bacteria, which are responsible for 80 percent of declared sepsis.
Although commonly known as “horseshoe crabs,” the ancient creature is actually more closely related to spiders, ticks and scorpions. (Pictured: Plant Image Library / C.C. 2.0)
Due to this unique nature, LAL is widely used by many testing institutions for the detection of Gram-negative bacteria. Unfortunately, the current blood-pumping process for wild slugs is still an unsustainable problem.
Although the animals are released into the ocean after being taken part of their blood, 30% of them are expected to die. For a species that is already on the endangered list, it is clear that we need to come up with a better way.
The good news is that researchers from Capley Biosystems, North Carolina, and the nearby Joint Institute of Nanoscience and Engineering have developed a circular aquaculture system.
It is able to stay in a multi-cylinder environment for a long time, receive a special diet, and regularly draw blood under sterile conditions. The latter process involves gently fixing, dipping its gills into water, and pumping blood through a paepiphacocatheter.
The report says the new technology has a near-zero mortality rate and is still healthy and healthy and healthy during captivity.
In fact, LAL reagents obtained from farmed individuals are significantly better in quality than in wild individuals and can even be used to detect sepsis in pre-treated human blood samples.
Scientists estimate that just 45,000 farms can meet all current diagnostic needs, leaving them to live off inhumane wild capture.
Details of the study have been published in the recent lying journal Frontiers in Marine Science.
Originally published as Horseshoe Crab Aquaculture as a Sustainable Endotoxin Test Source.
Finally, a previous study by Princeton University showed that harmless peptides collected from the skin of African claw frogs could also be an eco-friendly alternative to LAL.