Scientists have completed a three-year project to create a detailed 3D structural “map” of the brains of laboratory mice,media BGR reported. The model will help scientists better understand the effectiveness of treatments and tests conducted with rodents.
Lab mice are specially bred for testing purposes and are often the first animals to feel the effects of the drug, from Alzheimer’s disease to back pain, and all the treatments. With that in mind, it makes sense for researchers to learn as much as possible about the brains of mice, and a three-year project has just completed the most complete mouse brain “map” ever.
In a new paper published in the journal Cell, researchers have carried out incredible research into every structure of the mouse brain. The result of this work is a rich and detailed 3D model that other scientists can use in their own research work. Each piece of the virtual brain model has a label and coordinates, making it easy to explore its intricacies.
“This map is a really necessary resource that enables us to study ideas at the whole brain level,” Dr. Nick Steinmetz, a scientist who recently used the mouse brain “map” for his own research, said in a statement. “When you record hundreds of sites across the brain, this introduces a new scale of investigation. You have to have a larger view of where all the record points are, and the common coordinate framework is what makes this possible. “
Obviously, the model has incredible scientific value. It could help researchers better understand the effects of various experiments and trials on the mice they care for, and may even make it easier to develop treatments that are useful for humans.
The Allen Institute of Brain Science explains the exact contents of the video it released:
The video depicts data fusion in the CCF framework. The background grayscale image represents the average anatomical structure of 1675 individual samples, forming the basis of the common coordinate system. A color curve represents the line of the sample. The mouse cortex is a 3D drawing of layers organized, where connections between layers are usually perpendicular to the surface, indicating a hypothetical column of tissue.