Doctors in the UK have observed that there are five blood tests that can be used as markers for severe COVID-19 syndrome affecting some children. The syndrome, a mixture of toxic shock and Kawasaki disease, can be fatal for some children infected with the new coronavirus. A few weeks ago, doctors in the UK warned of the new COVID-19 syndrome, which has since been seen in other countries, including the US. In the UK and New York, as the number of cases increases, some children die from these unexpected COVID-19 complications. But doctors in the UK believe they have come up with a way to predict whether children will get COVID-19 syndrome.
So far, hundreds of cases have been reported worldwide, the Guardian reported. Doctors suspect that the immune system may overreact to the virus within a few weeks of the initial infection, sometimes within weeks of the infection. The syndrome includes persistent symptoms such as fever, rash, rash, abdominal pain and cold hands and feet. Physicians describe it as a mixture of toxic shock and Kawasaki disease. The most serious complications of this pediatric inflammatory polysacle syndrome include inflammation of the heart’s blood vessels, which can lead to a fatal coronary aneurysm.
Researchers from Imperial College London looked at blood tests in some sick children and found high levels of five blood compounds: ferritin, C-reactive protein (CRP), troponin, cerebral sodium peptides and D-dipolymers.
The first two are signs of inflammation, while the other three may be associated with heart damage and blood clotting. The latter is a phenomenon observed in adult patients as the cause of stroke and heart attack — two of the more unusual symptoms in COVID-19. According to a recent study, blood clotting in adults can also lead to complications.
“We know that these markers are present in patients with severe illness, and in some normal Kawasaki patients, these markers have lower levels,” Michael Levin, professor of pediatrics and international child health at Imperial College, told the Guardian. The doctor added that the five markers could help doctors determine whether a child has progressed to heart failure. In this way, they can determine which children must be transferred from the regional hospital to a specialist centre and then to the intensive care unit.
Professor Chris Whitty, the UK’s chief medical officer, allowed researchers to include the children in a European study called Diamonds, which looks at inflammatory diseases. Doctors will collect blood samples from children to study what markers can help predict the severity of the disease and understand genetics.
Doctors will also use an international database to add anonymous information to the study, including blood test results and treatments, so that others can see which treatments work.