On May 18, local time, U.S. biotech company Moderna announced that preliminary experimental data showed that all 45 participants had antibodies in their bodies, eight of whom were “neutralizing antibodies”, the most effective antibodies to the virus, Reuters reported.
According to the report, Moderna began clinical trials of the new corona vaccine on March 16, the first in the United States to conduct clinical trials. The team recruited 45 healthy volunteers to participate in the experiment, who were divided into three groups of 15 people and were vaccinated at 25 micrograms, 100 micrograms, or 250 micrograms. At present, the first phase of the first phase of the first two groups of volunteers have been published, 250 micrograms of the experimental results have not yet been revealed.
Moderna said participants who received 25 micrograms and 100 micrograms produced higher levels of antibodies than those in the blood of patients recovering from new coronary pneumonia, which proved that the vaccine was safe. Those who received 100 micrograms produced more antibodies than those who injected 25 micrograms.
Moderna’s vaccine has been approved for a second phase of clinical trials, and last week U.S. regulators opened a “fast track” to speed up regulatory review.
Moderna said that in the second phase of the clinical trial, the efficacy of the drug will be further tested to find the optimal dose of antibodies that can produce the body, and to study the validity of the antibodies. The company will abandon the 250 microgram dose to 50 micrograms. Reducing the dose required to generate immunity helps to save the dose of the vaccine needed for each injection, which means that more vaccines can eventually be produced.
According to US media reports, Moderna’s shares rose 20 percent after the announcement. U.S. President Donald Trump said the same day: “I saw the results, the results are amazing.” We’re going to be okay, and that’s one of the good things. So today is a big day. That’s a far cry from what it felt on Friday (when the stock market was volatile). Today is a very positive day. “
A U.S. biotech company announces new developments in new crown vaccine, Trump: Today is a big day