The United States plans to conduct a large-scale test that will recruit more than 100,000 volunteers to test about six of the most promising new coronavirus candidates in an effort to provide a safe and effective vaccine by 2020, Reuters reported Wednesday. The report says the general vaccine usually takes 10 years from development to testing, but plans are to shorten the overall time frame to several months in order to calm the outbreak as quickly as possible.
To achieve this goal, leading vaccine manufacturers in the research and development process have agreed to share data and lend their clinical trial network to competitors if their candidate vaccine development fails.
The report also mentions that in the past, vaccine development, first to conduct animal tests, and then for healthy volunteers to conduct a small safety test, and then a little large-scale research, the final stage of the large-scale testing of thousands of people. Only if these steps are completed will vaccine developers be able to produce millions of doses on a large scale.
However, many steps will overlap in the face of an pandemic, with large-scale testing expected to begin in July, with 2-3 million volunteers each targeting 20,000 to 30,000 volunteers for the vaccine, which has been shown to be safe in small early studies.
Dr. Larry Corey, a vaccine expert at the Fred Hutchinson Cancer Research Center in the United States, said there could be 100,000 to 150,000 people involved in the study, and he is helping design the tests. “Without safety, research will continue,” said Dr. Francis Collins, director of the National Institutes of Health. “
However, the report notes that this approach is risky because some security issues may only arise in large-scale trials. A joint Reuters/Ipsos survey shows Americans are concerned about the pace of vaccine development.