Experts, including the World Health Organization and Dr. Anthony Fauci, say the new coronavirus may never go away, which sounds shocking, but it’s not the whole story,media reported. The flu may never go away, even if we have a vaccine that provides temporary immunity. However, influenza is a highly controlled infectious disease. We have all kinds of proven treatments and we all know how to treat its symptoms and when to seek medical attention. COVID-19 is still a disease that lacks standard treatments, although doctors have been testing various effective treatments, including some promising vaccine candidates.
Other researchers are developing new drugs aimed at preventing virus replication and providing short-term immunity. These are antibody-based drugs that can improve the condition of COVID-19 patients by helping the immune system in PATIENTs with COVID-19. Antibody-rich plasma from COVID-19 survivors has demonstrated that this type of treatment is effective in severe cases.
Now, researchers in the UK have a new finding related to the immune response that could help doctors predict which COVID-19 cases will worsen. It may even provide them with a way to treat these severe cases. When doctors treating COVID-19 patients, they found that their T-cells were very small. It is an immune cell, also known as T lymphocytes, responsible for removing pathogens such as the new coronavirus.
Other researchers have found that T-cells play an important role in killing new coronaviruses, and that some patients may already have The kind of T-cells that respond to the virus immediately. This may be due to a previous infection of one of four other known human coronaviruses.
The BBC reported that scientists from the Francis Crick Institute, King’s College London and Guy and St Thomas’ Hospital looked at the immune cells in the blood of 60 COVID-19 patients and found very small numbers of T-cells. In a microliter of blood, 2,000 to 4,000 T-cells should usually be found. But in coVID-19 cases, the number drops to between 200 and 1200.
Manu Shankar-Hari, an intensive care consultant at Guy and St. Thomas Hospital, said that in about 70 percent of COVID-19 patients he saw in the intensive care unit, the number of lymphocytes per microliter in the blood was between 400 and 800. “When they start to recover, their lymphocytes start to pick up,” he told the BBC.
Adrian Hayday, a professor at the Francis Crick Institute, said it was clearly a “huge surprise”. T-cells “are trying to protect us, but the viruses seem to be doing something that catches people off guard because their numbers are plummeting.” “
“The exact cause of this interference — a ‘wrench’ in the T-cell system — is not clear to us at all. He said. “This virus is really doing something different, and future research — and we’re going to do it right away — needs to find out what the mechanism sonbys. “
The findings provide researchers with two useful ideas for managing COVID-19 severe cases. First, blood tests can be used to provide early indications of which patients may have serious complications. In addition to this “fingerprint test” of T-cells, the researchers will also study the effects of leukocyte interleukin 7 (IL-7), a drug that should increase the number of T-cells and hopefully improve recovery time.
Leukocyte interleukin 7 has been tested in a small number of sepsis patients, proving that it can increase the production of T cells. In the COVID-19 trial, patients who were hospitalized in the intensive care unit for more than three days with low lymphocyte counts were given the drug. “We want to get rid of the virus (when we increase the number of cells),” Shankar-Hari said. “As an intensive care doctor, I look after patients who are extremely unwell and we don’t have any direct and active treatment for the disease other than supportive care,” he said, adding that the trial was very encouraging for British doctors.