On June 3rd researchers at Harvard University, published in Nature, offered hope to hair loss and burn patients by using human stem cells to grow hair follicles and grow hair in mice,media reported. Hair loss and dissonation are mostly caused by damage to hair follicles, so the most effective way to treat them is to transplant new hair follicles. Researchers at Harvard University have made the treatment a success by using human stem cells to grow skin-like organs in a petri dish.
The researchers say the stem cells can form any type of skin tissue, and after transplanting them to mice that lack hair, more than half of the transplants grow 2 to 5 mm of new hair, which is almost identical to naturally occurring hair.
Professor Karl Koehler, a plastic surgeon at Harvard Medical School, said: “This suggests that organs can fuse with the mouse epidermis and form new hair-growing skin. These skin-like organs need to be cultured in a mixture of growth factors and other chemicals for 4 to 5 months to produce the skin epidermis and dermis. “
Because the structure and texture of the skin are very complex, it is also one of the most difficult organs to imitate. It has appendages such as hair follicles and glands, which are essential for regulating body temperature and body fluids, which help protect the body from disease and injury and control feelings of touch and pain.
Professor Kohler said rebuilding skin appendages in cultures and bioengineering grafts was a challenge to be addressed because of the complexity of the skin. Now that we have solved this problem, it can be used for hair loss treatment.
In addition, skin organs may also treat other difficult items, including cancer. Researchers have developed a model for studying the cytodynamics of skin organ development to explore a range of treatments for hereditary skin diseases and cancers. Once the method is used in clinical practice, those with hair loss, scars, hereditary skin diseases, burns, etc. will be revolutionized.