It is well known that vaccines need to be refrigerated and stored, and they are generally safe between 2 and 8 degrees Celsius. As a result of this limitation, millions of children around the world have missed out on vaccinations, but this situation is now expected to be resolved. Scientists at the University of Bath in the UK have now found a way to prevent vaccines from failing at room temperature,media reported on June 8. By wrapping the vaccine protein molecules in a silicon dioxide shell, even if heated to 100 degrees C or stored at room temperature for up to three years, it does not damage its structure.
A team of researchers from the University of Bath and the University of Newcastle in the UK have teamed up to develop a technique that uses a silicon dioxide coating to protect the vaccine. Two years ago, the pioneering technology was supposed to work in the laboratory, and it has proven its effectiveness in practical application.
In the study, the researchers mailed two tetanus vaccines by regular mail from Barnes University to The University of Newcastle (about two days away). One vaccine is protected with a coating and the other is unprotected.
It was found that the immune response was successfully triggered when the vaccine was injected into the mice with a coating, while the unprotected vaccine was injected into the mice and did not trigger the immune response.
Dr Asel Sartbaeva, of the University of Bath, said: “The results are exciting and this new technology not only preserves the protein structure of the vaccine, but also preserves the immunogenicity of the vaccine.” Next, we’ll want to develop a coating for the entire DTP trivalent vaccine, making it easier for children around the world to get it. “
It is understood that up to 50% of vaccines are discarded before use due to exposure to high temperatures. According to the World Health Organization (WHO), 19.4 million babies were not vaccinated against routine life-saving vaccinations in 2018.