Fried chicken, grilled meat, milk tea, fat house happy water… Clearly know not to eat more, how to partial can not control this mouth? It is said that there may be “worms” in the stomach. In a recent research paper published in the leading academic journal Nature, several scientists at the National Institutes of Health (NIH) demonstrated that preference for what they eat is really controlled by gut microbes, at least in some lower-class animals.
The scientists chose nematodes as their subjects to study the effects of gut bacteria on animal behavior. Nematodes have long been used by scientists to study various aspects of basic biology, and are now a model organism for studying intestinal flora.
Small nematodes (Caenorhabditis elegans) are well-known model creatures in biological research
In the natural environment, nematodes are exposed to a wide variety of bacteria. Some bacteria are nutritious and are a delicacy of nematodes, while others make nematodes sick and are the health enemies of nematodes. Although nematodes are small, they have also learned to distinguish between good and bad, and can avoid pathogenic bacteria according to the smell of bacteria. For example, some bacteria secrete inol, and high concentrations of inol molecules are evasive odor signals for nematodes.
Interestingly, after feeding the nematodes different bacteria, the researchers observed that some of the bacteria had changed their preference for odor. Specifically, nematodes, which grow with Providen and feed on Providen, are no longer so evasive about the original “disgusting” sinol, and even seem to be a little fond of actively moving to the sinol molecule.
The Providen strain (JUb39) gives nematodes a “genuine” sense of high concentrations of inol
Further examination found that although many bacteria are crushed when swallowed by nematodes, some of them enter the nematode’s intestines intact and thrive. And nematodes, who like sinol, have some live Providence bacteria in their intestines.
After a detailed analysis of the bacteria, which are implanted in the intestines, the researchers found that they produced a chemical called tyamine. And this chemical, metabolized in the body of the online worm, becomes a neurotransmitter octopus amine that regulates the neural activity of nematodes. Octopus amine, on the other hand, regulates nematodes’ aversion to odors. In other words, Providence in the gut makes nematodes more resistant to the smell of sinol.
When the nasty smell becomes unobxiant, it’s not hard to imagine that nematodes’ preferences naturally change when they choose food. The researchers tested this through a group of food selection experiments. In different bacterial meals to choose from, compared to nematodes that feed on other bacteria from an early age, nematodes that feed on Providen bacteria from an early age will be more likely to eat Providen bacteria under the influence of gut bacteria – perhaps for nematodes, which is the taste of “childhood”?
Providence feeds large nematodes in the face of food and makes different choices than other nematodes
“We continue to find that gut bacteria play an unexpected role outside the gut.” Dr Robert Riddle, ni’s project director at the NIH, commented, “In this story, gut bacteria affect nematodes’ perception of the environment and attract animals to the likes of the same bacteria outside. Those gut bacteria make them look more delicious. “
In summary, in a simple pattern of online worms, gut bacteria affect the neural activity of host animals through secreted chemicals, which in turn affect food choices. The results apply only to nematodes, and in higher animals, how gut bacteria affect animals’ preferences for smell and food requirefurther research and exploration. Who do you think is in control when you find yourself unknowingly in front of certain foods?