Researchers develop hybrid antibiotics: can kill bacteria through biofilms

According tomedia reports, the bacteria themselves are not difficult to kill. The problem is that these cunning bacteria build up colonies behind a barrier known as a biofilm, and antibiotics specifically designed to deal with them are hard to penetrate. Now researchers from the Queensland University of Technology (QUT) have developed a hybrid antibiotic that can penetrate some biofilms.

Researchers develop hybrid antibiotics: can kill bacteria through biofilms

According to Anthony Verderosa, a member of the study and lead author of the study, biofilms are a viscous coating that usually prevents conventional antibiotics from coming into contact with bacterial cells, and now they have developed a new antibiotic that can trick the biofilm into passing through it.

It is understood that the new antibiotic is a widely used antibiotic – ciprofloxacin and a mixture of compounds called nitrogen oxides. The latter has recently been found to be effective in removing biofilms, allowing ciprofloxacin to enter and kill bacteria.

Researchers develop hybrid antibiotics: can kill bacteria through biofilms

Anthony Verderosa (left) and Makrina Totsika (right) were co-investigators on the study

The team tested the mixture on a biofilm made from Staphylococcus aureus. As a result, the researchers found that it could effectively penetrate biofilms and eradicate bacteria, and that, better yet, it would require less cyclate sand than usual. In addition, they found no signs of toxicity in healthy human cells.

Researchers say they are preparing for the next human trial.

The study was published in Anti-Conocoy and Newsy.

Add a Comment

Your email address will not be published. Required fields are marked *