Interestingly, caffeine has long been considered an effective appetite suppressant and has been shown to be effective in accelerating the body’s fat metabolism,media reported. Now, a new study from the University of Illinois has found another interesting mechanism that explains the weight loss of caffeine. It is reported that the object of this study is a popular South African drink – Madei tea.
Madetea is a stimulant popular in Latin American countries and, although it contains less caffeine than a standard cup of coffee, it has a stronger excitatory effect than tea. Since madetea contains a large number of new bioactive phytochemicals other than caffeine, the main purpose of this study is to determine whether the anti-obesity effect of madetea is related to caffeine or to other ingredients in tea.
To do this, the researchers conducted a series of animal experiments, feeding mice high-fat/high-sugar foods and supplementing them with caffeine in the form of tea, coffee or synthetic sources. They found that mice who ate any form of caffeine gained less overall than mice who ate the same unhealthy diet but drank decaffeinated tea.
Caffeine seems to be the key anti-obesity agent for madetea. To understand how caffeine affects fat cells, the researchers also conducted extensive research on cell culture. The study found that deasperitased, regardless of the source, which reduced lipid accumulation in fat cells by 20 to 41 percent.
What’s more, the researchers found that caffeine reduces the expression of several genes associated with lipid metabolism in adipose tissue and liver tissue. In the study, researchers identified three genes associated with the production of LDL cholesterol in the liver.
Co-author of the new study, Elvira Gonzalez de Mejia, said: “Due to the regulation of fat tissue and certain fat-forming enzymes in the liver, caffeine from marde tea or through other sources can mitigate the negative effects of a high-fat, high-sucrose diet on the body. “
While it’s unclear whether caffeine will be effective in fighting obesity in real human environments, the researchers behind the new study believe their findings at least confirm the drug’s potential.
The study was published in The Journal of Functional Foods.