The healthier the sleep pattern, the lower the overall risk of cardiovascular disease, and the risk of coronary heart disease and stroke, according to a study published in the European Heart Journal by the team at Tulane University and Peking University. The team from Tulane University and Peking University in the US analyzed data from 385,000 subjects with no cardiovascular history in the UK biosample pool.
The researchers analyzed blood samples from subjects and scored high, medium and low genetic risk scored on cardiovascular disease. The researchers also collected participants’ sleep patterns, duration, insomnia, snoring and excessive daytime drowsiness and rated their sleep health.
During an average of 8.5 years of follow-up, the researchers recorded 4,667 cases of coronary heart disease and 2,650 strokes, for a total of 7,280 cases.
The results showed that the most healthy sleepers (who slept early, slept 7-8 hours a night, did not sleep, didn’t snooze, and had a good mental state during the day) had a 35 percent lower risk of cardiovascular disease and a 34 percent lower risk of coronary heart disease and stroke.
Further analysis of sleep and genetic factors, the researchers found that people with high genetic risk and poor sleep habits were 2.5 times more likely to develop coronary heart disease than those with low genetic risk and healthy sleep habits, and 1.5 times more likely to have a stroke.
The researchers note that healthy sleep can offset some of the genetic risks. In contrast, people with low genetic risk but not a good sleep ingress were more likely to have a 67 percent and 63 percent higher risk of coronary heart disease and stroke, respectively, compared to those with high genetic risk but good sleep habits.
The mechanism of effect between sleep and cardiovascular disease risk is unclear, the researchers note. Sleep disruption may disrupt the body’s hormone or metabolic regulation, affect the body’s immune response, exacerbate inflammation, destroy the body’s natural circadian rhythm…
The researchers suggest that people with high genetic risk can reduce risk by improving sleep health. Early, sleep 7-8 hours a night, no insomnia, no snoring, good mental state during the day, the study of healthy sleep for the general population to provide a positive reference for sleep.