On the progress of the pathogen identification of the outbreak of viral pneumonia in Wuhan, reporters today learned from the preliminary assessment team of pathogen test results that, as of 21:00 on January 7, 2020, the laboratory detected a new type of coronavirus, and obtained the whole genome sequence of the virus. A total of 15 cases of positive results of the new coronavirus were detected by nucleic acid testing method, and the virus was isolated from a sample of 1 positive patient, and the typical coronavirus pattern was shown under the electromirror.
The Group of Experts believes that the pathogen of this unexplained case of viral pneumonia was initially determined to be a new type of coronavirus.
Tissue laboratory using genome sequencing, nucleic acid detection, virus isolation and other methods of patients’ alveoli irrigation liquid, pharynx swabs, blood and other samples for pathogenic testing.
The Group indicated that the identification of the pathogens that cause an epidemic disease usually meets the following points:
(1) The suspected pathogens must be found in the patient, and the pathogen nucleic acid can be detected in the clinical samples of the patient;
(2) Successful separation to pathogens from clinical samples of patients;
(3) Isolated pathogens infected with host animals can cause the same symptoms of the disease. The antibody titer of the pathogen in the patient’s recovery serum is 4 times higher, which can help determine the pathogen.
Evidence of nucleic acids, genomes and antibodies found in patients can be done in the short term. Scientific studies such as the separation of pathogens and the identification of pathogenicity can take weeks. Development of special drugs and vaccines for a new pathogen could take years to complete. The Group of Experts believes that the pathogen of this unexplained case of viral pneumonia was initially determined to be a new type of coronavirus, the next step is to combine pathogen research, epidemiological investigation and clinical performance for expert research.
Coronary virus is a kind of pathogen that mainly causes respiratory and intestinal diseases. The surface of this virus particle has many regularly arranged protrusions, and the entire virus particle is like a crown of the emperor, hence the name “coronavirus”. In addition to humans, coronavirus can also infect pigs, cattle, cats, dogs, crickets, camels, bats, mice, hedgehogs and other mammals and a variety of birds. So far, there are six known human coronaviruses. Four of these coronaviruses are more common in the population, less pathogenic, and generally cause only mild respiratory symptoms similar to the common cold. Two other coronaviruses, severe acute respiratory syndrome (SARS) and MERS coronaviruses, also known as SARS and MERS, can cause severe respiratory diseases. The new coronavirus that caused the outbreak is different from the human coronavirus found, and further scientific research is needed.