Will drug resistance also pass? The consequences of overuse of antibiotics are worse than thought.

In many people’s eyes, whether it is a cold fever, or headache brain fever, it seems that as long as eat a little “Amosilin”, the condition will improve. But frequent antibiotic use often results in bacteria becoming resistant, so doctors will prescribe more antibiotics to kill the bacteria by at least one. However, a new report published in Science suggests that this could make things worse.

Will drug resistance also pass? The consequences of overuse of antibiotics are worse than thought.

DOI: 10.1126/science.aay3041

The report, by researchers at the Hebrew University and Shaare Zedek Medical Center, suggests that the use of multiple antibiotics in patients with bacterial infections may promote the spread of drug resistance. The researchers looked at the treatment of a patient with Staphylococcus aureus in his blood. At first, the doctor treated the patient with vancomycin. When vancomycin does not relieve the condition, the doctor adds lifupine to the treatment. Eight days later, doctors treated dattomycin instead of vancomycin.

In the process, the researchers took blood samples from patients to determine the effectiveness of the treatment, which allowed them to individually test the level stoacity of microorganisms in the blood. It was found that dattomycin killed bacteria more slowly after combining the drug, which meant that the bacteria were evolving resistance to dattomycin. The same was observed by the researchers while testing for other types of bacterial infections. Based on this, the researchers believe that combining antibiotics with patients can make bacteria resistant to drugs that are still in effect.

According to a 2014 World Health Organization report, 10 million people worldwide will die each year from antibiotic-resistant infections each year. While researchers have been looking for ways to address bacterial resistance, it is important to take care not to overuse antibiotics to avoid more serious consequences.

Resources:

Study s suggests giving infected patients combinations of the antibiotics may promote resistance

Effect of tolerance on the evolution of the antibiotic resistance under under drug combinations