The rampant SARS virus comes from the beaver and is transmitted from the fruit beaver to the human. The new coronavirus, which caused the current outbreak of pneumonia and was first discovered in Wuhan and named 2019-nCoV, may have come from snakes. Following two academicians, Zhong Nanshan and GaoFu, said the Wuhan pneumonia virus came from wild animals, a research paper published online by Chinese scholars on January 22th narrowed the range of the animals to the snake.
The title of the paper is “The homologous recombination of the new coronavirus fibrous protein may have contributed to cross-species transmission from snake to human” (Homologous recombination withthe in the spike glycoprotein of the newly Coronavirus may boost crossspecies transmission from snake to human, by researchers from Peking University, Guangxi University of Traditional Chinese Medicine, Ningbo University, Wuhan Institute of Biological Engineering, 22 online in the English-language academic journal Journal of Medical Virology.
The researchers analyzed the genetic sequences of the aforementioned coronavirus to evaluate the RSCU in those sequences, the paper said. The aforementioned coronavirus RSCU was then compared with RSCU of the genetic sequence of animals in different species.
The findings suggest that snakes are most likely to be animals that carry the new coronavirus compared to other animals, the paper said.
The full name of the RSCU is “the relative use of synonymous cryptography” (or use frequency, use bias, relative syibii codon). It refers to the degree of preference (bias) that the same gene sequence is used for synonymous cositends when coding an amino acid.
Two or three different sequences of genes may correspond to the same amino acid, and these different gene sequences are called synonymous cosies.
Different species have different preferences for the aforementioned gene arrangement. In other words, the frequency of these genes being arranged in different species varies, and therefore reflects the differences in species. This comparative analysis method is used to analyze the evolution and recombination of viruses, or RSCU methods.
In addition, the aforementioned paper said that the new coronavirus is a recombinant virus, the recombinant region of the virus is located in the virus’s protrusion protein. The protein acts like a tool to identify the surface receptors of the host cell and pry open the cell’s protective door. Part of the genetic sequence of the new coronavirus comes from the bat coronavirus.