Nature calls for coronavirus research to be shared

At a critical time for the outbreak, Nature, the world’s top journal, has published an editorial calling on all coronavirus researchers to keep sharing and openness. The British government has announced that it will invest 20 million pounds in the development of a new coronavirus vaccine to help China fight the outbreak. The money will also help British women scientists work for three hours to design a new coronavirus vaccine. As of the time of writing, 24363 cases of new coronavirus infection were confirmed nationwide, 23,260 cases were suspected, 492 deaths were reported and 897 cases were cured.

At a critical time for the outbreak, Nature, the world’s top journal, has published an editorial calling on all coronavirus researchers to keep sharing and openness.

Nature calls for coronavirus research to be shared

“As new coronaviruses continue to spread deadly, researchers must ensure that their work in this outbreak is shared quickly and publicly. “

Nature signs joint statements with nearly 100 institutions to ensure rapid sharing of research data and findings

At present, the new coronavirus has become “a public health emergency of international concern”. In China, some cities have been cordoned off and new hospitals have been set up in the outbreak of Wuhan.

Along with medical staff, Chinese researchers are playing a vital role. Epidemiologists are working to update estimates of the number of cases, are sequencing the genome samples of pathogens and sharing the results.

In two papers in the journal Nature, a team led by researchers at the Wuhan Virus Research Institute and Fudan University in Shanghai confirmed that the virus is similar to the virus that causes Severe Acute Respiratory Syndrome (SARS) and that there is evidence that it originated in bats.

Nature calls for coronavirus research to be shared

Address: https://www.nature.com/articles/s41586-020-2012-7

The team in Wuhan analyzed samples of the virus genome soutcomes of a small number of patients who worked at a local seafood market, where the first case came from.

Eventually, the team found that the sequence of the new coronavirus nCoV-2019 that ravaged Wuhan was as consistent as 96% at the genome level with a bat coronavirus sequence.

Nature calls for coronavirus research to be shared

Address: https://www.nature.com/articles/s41586-020-2008-3

The team at Fudan University sequenced a sample of an infected seafood market worker. Genomic analysis showed that the virus was closely related to a group of SARS-like coronaviruses previously found in bats in China.

In the first few days after the outbreak, Nature confirmed that the reporting research and data would not affect contributions to Nature magazine. Nature and its publisher, Springer Nature, have now signed a joint statement with other publishers, funders and scientific associations to ensure that research data and findings related to coronaviruses can be shared quickly. In a statement, Agence Nature and others are committed to working together to ensure that:

All peer-reviewed research publications related to outbreaks should be immediately available or at least free of charge during the outbreak.

Research related to the outbreak was found to be shared with the World Health Organization (WHO) as soon as the journal was submitted.

The results of the study can be obtained through the pre-print server prior to publication of the journal, or through a publicly available platform for the paper prior to peer review, and a clear indication of the availability of the underlying data.

Researchers share medium- and final research data related to outbreaks, as well as protocols and standards for data collection, as quickly and extensively with public health and research groups and the World Health Organization.

(共同签署这项声明的还包括中国疾病预防控制中心、英国医学科学院、arXiv、比尔和梅琳达·盖茨基金会、爱思唯尔、美国食品药品监督管理局、美国国立卫生研究院、柳叶刀、新英格兰医学杂志等机构,详见:https://wellcome.ac.uk/press-release/sharing-research-data-and-findings-relevant-novel-coronavirus-ncov-outbreak)

The first priority now is to stop the spread of the virus and help those affected. This includes understanding how viruses spread from person to person, increasing the availability of diagnostic equipment, and accelerating vaccine development.

In addition, questions have been raised as to whether there has been a delay in the issuance of the alert. If we want to learn our lesson next time, we must answer truthfully.

Increased regulation of animal markets is also crucial, as negligence increases the risk of new viruses being transmitted from animals to humans.

And investment must be invested to better surveillance of diseases in the poorest countries, which is the main cause of the World Health Organization’s declaration of the virus as a “public health emergency of international concern”.

For researchers, the message is simple: work hard to understand and fight the epidemic;

UK announces investment of 20 million pounds to develop new crown vaccine, with female scientists designing vaccine in three hours

At the moment, everyone is looking forward to the emergence of vaccines and special drugs for the new coronavirus, and the openness and sharing of research that Nature is calling for will speed up the process.

The British government announced on February 3rd that it would invest 20 million pounds in the development of a new coronavirus vaccine to help China fight the outbreak. At the same time, the British government also announced that it will increase funding to pioneer the study of various types of virus vaccines, diagnostics and antiviral therapies to deal with future virus-induced sudden public health safety incidents.

The uk government’s money will also help fund the work of Dr Kate Broderick, a 42-year-old Scot based in California who is working to make a coronavirus vaccine.

Nature calls for coronavirus research to be shared

Kate Broderick

After the CDC released information about the strain of the new coronavirus (2019-nCoV), Dr. Kate Broderick led the team to quickly design the vaccine, now called INO-4800, which is racing for preclinical testing, during which time “only two hours of sleep a day”.

Her team, using a new type of DNA technology to develop and test in animals, plans to enter human clinical trials of the INO-4800 vaccine by the beginning of the summer.

Kate says his team can develop the virus DNA sequence immediately, thanks to the rapid chinese provision of the virus’s DNA sequence. “We designed the vaccine in three hours through the computer technology in the lab. “

Nature calls for coronavirus research to be shared

“The newly designed DNA drug vaccine is innovative because it uses the DNA sequence of the virus to target specific parts of the pathogen, and it is believed that the human body will react most strongly to those parts. “

“We then use the patient’s own cells to become a vaccine factory, strengthening the body’s own natural response mechanism. “

Kate’s Inovio pharmaceutical company says that if scheduled, it would be the fastest ever to develop and test a new vaccine in the event of a virus outbreak, much faster than the time it takes to develop a vaccine against SARS and the Middle East Respiratory Syndrome (MERS) virus.

Related links http://www.scots

https://www.bbc.com/news/health-51352952

https://www.thetimes.co.uk/article/the-scientist-racing-to-find-a-vaccine-to-the-coronavirus-g5qjkj8q6