Zhejiang CDC: Tea can kill and effectively inhibit the replication of new coronaviruses in cells

With the support of the Zhejiang Science and Technology Department’s “Research on key technologies in the prevention and control of the new coronavirus virus outbreak pneumonia”, zhejiang Provincial Center for Disease Control and Prevention researchers Lu Yiyou, Feng Yan and other experts released the latest research results: daily drinking tea at the cellular level has the role of anti-new coronavirus.

Zhejiang CDC: Tea can kill and effectively inhibit the replication of new coronaviruses in cells

The research team chose green tea, Tieguanyin and dahong robes, said to take the above types of tea 2 grams, with 50mL boiling water (measured 90 degrees C) soaked 30min, at this time the concentration is 40 mg/ mL (i.e., usually tea when making tea), cooled to room temperature, with cell maintenance liquid diluted to the experimental concentration.

First, in vitro virus-killing tests were carried out with different concentrations of tea (2.5-10 mg/mL), and boiled water and commercially available drinking water were set up as experimental control groups. Different concentrations of tea, as well as the control group and 100TCID50 of the new coronavirus respectively, infected Vero cells and cultured for 48 hours, to determine the level of viral nucleic acid proliferation in each group.

The results showed that the nucleic acid proliferation of the new coronavirus in the tea water treatment group was reduced by 10,000 to 100,000 times compared with the virus control group without tea water treatment, while the propagation condition of the boiling water and commercially available drinking water control group used for brewing was consistent with that of the virus control group, indicating that the tea had good out-of-cell killing effect on the new coronavirus. Secondly, the research team also used 0.25 to 2 mg/mL of tea to treat the cells after 1 hour of the new coronavirus infection, cultured 48 hours later, found 0.25 mg/mL of green tea, 1 to 2 mg/mL of the big red robe and 0.5 to 1 mg/mL of Tieguanyin have the ability to inhibit the replication of the new coronavirus, inhibition effect with the increase in the concentration of tea water.

For the first time in this study, tea, with tea polyphenols (including catechins), was found to have good extracellular killing and intracellular proliferation inhibition for new coronaviruses in in vitro cultured cells.

Tea drinks have been used in China for thousands of years with disease prevention, treatment and health of healthy drinks, so the team believes that drinking tea may be beneficial to the prevention of new coronary pneumonia.