First large CT sample analysis of new crown cases: rapid lung lesions within 3 weeks of onset

On 24 February 2020, local time, Radiological Froms 81 patients with COVID-19 pneumo, a joint team of radiology departments of Concord Hospital affiliated with Tongji Medical College of Huazhong University of Science and Technology and Wuhan Jinyintan Hospital Nia in Wuhan, China: a descriptive (imagery of 81 new crown pneumonia cases in Wuhan: a descriptive study) published in the Lancet sub-journal The Lancet Infectious Disease us Diseases).

This paper is also the first to be published in a well-known journal of the new coronary pneumonia large sample CT imaging research paper.

First large sample paper on CT in new crown cases

The researchers performed continuous chest CT scans of patients with new coronary pneumonia in the two hospitals (confirmed by next-generation sequencing or RT-PCR) and conducted retrospective analysis of their imaging characteristics and distribution.

Depending on the interval between the time of the onset of symptoms and the first CT scan, 81 patients admitted between December 20, 2019 and January 23, 2020 were divided into 4 groups: 15 (subclinical patients) in group 1, 21 in group 2 (?1 week), 30 cases in group 3 (1-2 weeks), Group 4 15 (2-3 weeks).

First large CT sample analysis of new crown cases: rapid lung lesions within 3 weeks of onset

The basic characteristics and symptoms of 81 patients

The specific data obtained by the researchers are as follows:

The average number of lesions in all patients was 10.5, Group 1 2.8, Group 2 11.1, Group 3 13.0, Group 4 12.1;

All patients with lung abnormalities were mainly bi-sided (64 cases, 79%), peripheral (44 cases, 54%), boundary confusion (66 cases, 81%), grinding glass shadow (53 cases, 65%), mainly affecting the lower right lung (225 out of 849 sections, 27%);

Group 1 and 2 had more patients with milled glass shadow: 1st group had one-sided lung abnormalities (9 cases, 60%), multi-focus (8 cases, 53%), milled glass shadows (14 cases, 93%), and group 2 lung abnormalities were two-sided (19 cases, 90%), diffuse (11 cases, 52%), grinding glass (17 cases, 81 % of %, group 3 grinding glass shadow 17 cases (57%), group 4 grinding glass shadow 5 cases (33%);

Groups 3 and 4 had more patients with real and mixed lesions: 12 (40%) in group 3 and 8 in group 4 (53%).

First large CT sample analysis of new crown cases: rapid lung lesions within 3 weeks of onset

In fact, the team focused on patients with a history of history. The following image shows a different level of CT image of a 60-year-old male patient with chronic lung disease (tuberculosis) who died of respiratory distress on the 12th day of admission to hospital. According to CT images on the 8th day of their illness, the two lungs are visible in a wide range of milled glass shadows, which affect almost the entire lower lower leaf, most of the upper and right lung, “white lung” (the lung is a large white shape, generally the lung is invaded by inflammation of the lungs), accompanied by air bronchographi.

First large CT sample analysis of new crown cases: rapid lung lesions within 3 weeks of onset

The paper points out that the chest CT of patients with new coronary pneumonia will show pulmonary leachate lesions, and asymptomatic infected people will also exhibit chest CT imaging abnormalities – within 1-3 weeks of the onset of the disease, the lesions rapidly progress from one-sided, pervasive lesions to double-lung diffuse abrasive glass shadow, and later combined real changes.

It can be seen that imaging examination combined with clinical and laboratory examination will contribute to the early diagnosis of new coronary pneumonia.

What does CT tell us?

In fact, the above-mentioned research has also been recognized by peers.

On February 24, Elaine Y P Lee, radiologist at the Li Ka-shing School of Medicine at the University of Hong Kong, also published the Lancet Infectious Diseases, entitled “New Coronapneumonia: What Does CT Tell Us?” article.

First large CT sample analysis of new crown cases: rapid lung lesions within 3 weeks of onset

This article confirms the team’s large sample CT study, which supports the evolution of CT imaging at different stages of the patient’s clinical symptoms:

CT is an important method for detecting new coronary pneumonia, even in asymptomatic patients. CT testing is especially important when nucleic acid test results are falsely negative.

In fact, some experts have questioned the accuracy of CT imaging results, but there is no denying that CT’s early diagnosis of new coronary pneumonia is still positive.